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Code
OSA00192W
$240USD
ID Tag
Rb1877-141012-WS
Immunogen
A synthetic peptide from aa region 850-900 of human ABCA1 conjugated to blue carrier protein was used as the antigen. The peptide shares 94% identity with mouse and rat sequences.
Accession
Also known
ATP-binding cassette sub-family A member1, CERP, ABC1, Cholesterol efflux regulatory protein, ATP-binding cassette 1
Target
FUNCTION: cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.
Defects in ABCA1 are a cause of high density lipoprotein deficiency type 1 (HDLD1)
Defects in ABCA1 are a cause of high density lipoprotein deficiency type 2 (HDLD2)
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Widely expressed, but most abundant in macrophages.
Defects in ABCA1 are a cause of high density lipoprotein deficiency type 1 (HDLD1)
Defects in ABCA1 are a cause of high density lipoprotein deficiency type 2 (HDLD2)
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Widely expressed, but most abundant in macrophages.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Qiu Y, et al. Genomics 73:66-76(2001)
2. Brousseau M.E, et al. J. Lipid Res. 41:433-441(2000)
2. Brousseau M.E, et al. J. Lipid Res. 41:433-441(2000)
Limitation
For research use only
Related
products
products
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Code
OSA00192W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ABCA1.
Spcs X-react.
Human. Other species not yet tested but expected to work in mouse and rat.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00192W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to ABCA1 (850-900)
