Code
OSA00191W
$240USD
ID Tag
Rb1876-141012-WS
Immunogen
A synthetic peptide from aa region 1200-1300 of human ABCA1 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
ATP-binding cassette sub-family A member1, CERP, ABC1
Target
FUNCTION: cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.
Defects in ABCA1 are a cause of high density lipoprotein deficiency type 1 (HDLD1)
Defects in ABCA1 are a cause of high density lipoprotein deficiency type 2 (HDLD2)
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Widely expressed, but most abundant in macrophages.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Qiu Y, et al. Genomics 73:66-76(2001)
2. Brousseau M.E, et al. J. Lipid Res. 41:433-441(2000)
Limitation
For research use only
Related
products
Code
OSA00191W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ABCA1.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.