Code
OSD00053W
$240USD
ID Tag
Rb1860-270812-WS
Immunogen
A synthetic peptide from aa region 150-200 of human DRAM2 conjugated to an immunogenic carrier protein has been used as the antigen.
Accession
Also known
DNA damage-regulated autophagy modulator protein 2, Transmembrane protein 77, TMEM77
Target
FUNCTION: Induces apoptotic cell death when coexpressed with DRAM1.
SUBCELLULAR LOCATION: Lysosome membrane; Multi-pass membrane protein
Tissue specificity: Expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Not detected in brain or thymus.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Park S.M, et al. Biochem. Biophys. Res. Commun. 390:1340-1344(2009)
Limitation
For research use only
Related
products
Code
OSD00053W
$240USD
Unit size
150 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. Use at a dilution of 1 : 200 to 1 : 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for DRAM2.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.