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Code
OSS00332W
$240USD
ID Tag
Rb1840-180812-WS
Immunogen
A synthetic peptide from aa region 5-50 of mouse SLC36A1 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Proton-coupled amino acid transporter 1, Proton/amino acid transporter 1, PAT1, Solute carrier family 36 member 1
Target
FUNCTION: Neutral amino acid/proton symporter. Probably involved in the efflux of lysosomal proteolysis products such as L-proline, L-alanine and glycine from the cell. May play a role in specifying sites for exocytosis in neurons.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note: In neurons, colocalizes with the exocyst complex in the axonal processes.
TISSUE SPECIFICITY: Widely expressed and predominantly expressed in brain. Within the brain, expression restricted to neurons and not detected in glial cells. Abundant in regions rich in neurons using glutamate and GABA such as Purkinje cells in the cerebellum and pyramidal cells in the hippocampus.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note: In neurons, colocalizes with the exocyst complex in the axonal processes.
TISSUE SPECIFICITY: Widely expressed and predominantly expressed in brain. Within the brain, expression restricted to neurons and not detected in glial cells. Abundant in regions rich in neurons using glutamate and GABA such as Purkinje cells in the cerebellum and pyramidal cells in the hippocampus.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Chen Z, et al. J. Physiol. (Lond.) 546:349-361(2003)
Limitation
For research use only
Code
OSS00332W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC36A1.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00332W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to SLC36A1
