Code
OSS00325W
$240USD
ID Tag
Rb1839-180812-WS
Immunogen
A synthetic peptide from aa region 30-100 of human SLC25A6 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
ADP/ATP translocase 3, ADP,ATP carrier protein 3, ADP,ATP carrier protein, isoform T2, ANT 2, Adenine nucleotide translocator 3, ANT 3, Solute carrier family 25 member 6
Target
FUNCTION: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein. Note: The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria
The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1.Houldsworth J, et al. Proc. Natl. Acad. Sci. U.S.A. 85:377-381(1988)
Limitation
For research use only
Code
OSS00325W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC25A6, 5
Spcs X-react.
Human. Other species not yet tested but expected to work in rat and mouse.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.