Glutamate receptor 4 antibody, Ionotropic Glutamate receptor 4 antibody, GRIA4 antibody, AMPA 4 antibody, GLUR4 antibody

Primary Antibodies

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSA00183W

$240USD

ID Tag

Rb1820-150712-WS

Immunogen

A synthetic peptide from aa region 150-250 of human Glutamate receptor 4 (AMPA 4) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

AMPA4_RAT
AMPA4_MOUSE
AMPA4_HUMAN

Also known

GRIA4, Glutamate receptor 4, GluR-4, GluR-D, Glutamate receptor ionotropic, AMPA-selective glutamate receptor 4, GLUR4

Target

FUNCTION: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction âº synapse âº postsynaptic cell membrane; Multi-pass membrane protein.
Tissue specificity: Detected in cerebellum (at protein level).

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Kato A.S, et al. Neuron 68:1082-1096(2010)

Limitation

For research use only

Code

OSA00183W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for AMPA 4.

Spcs X-react.

Rat, human, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSA00183W