Rb1796-260512-WS

A synthetic peptide from aa region 70-170 of mouse FOX3 conjugated to blue carrier protein was used as the antigen.

FOX3_MOUSE
FOX3_RAT

RNA binding protein fox-1 homolog 3, Fox-1 homolog C, RBFOX3, FOX3/NeuN

FUNCTION: RNA-binding protein that regulates alternative splicing events. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm
Tissue specificity: Widely expressed in brain, regions including cerebral cortex, hippocampus, thalamus, caudate/putamen, cerebellum, as well as in the spinal cord (at protein level). Not expressed in all neuronal cells within a region, in cerebellum, expression is absent in Purkinje cells (at protein level). Expressed in the retina in the ganglion cells and some cells in the inner nuclear layer, but absent from the photoreceptor cells and most cells in the inner nuclear layer (at protein level).

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. Kim K.K, et al. J. Biol. Chem. 284:31052-31061(2009)
2. Lind D, et al. J. Neurosci. Res. 79:295-302(2005)

For research use only

100 µl

Unconjugated antibody

NZ white rabbit

Whole serum

Polyclonal

Polyclonal, whole serum

IHC, WB. A dilution of 1 : 1000 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specific for FOX3.

Mouse, rat. Other species not yet tested.

Lyophilised

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

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- Click to download the Material Safety Data Sheet