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Code
OSA00178W
$260USD
ID Tag
Rb1781-290412-WS
Immunogen
A synthetic peptide from aa region of 580-660 of human Anoctamin 10 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Transmembrane protein 16K, ANO10, TMEM16K
Target
FUNCTION: May act as a calcium-activated chloride channel.
Defects in ANO10 are the cause of spinocerebellar ataxia autosomal recessive type 10 (SCAR10)
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Highly expressed in the brain. Intermediate levels in the retina and heart and low levels in the placenta, liver, lung, duodenum, kidney, testis and spleen. In brain areas, highest expression in the frontal and occipital cortices and in the cerebellum. Lower expression in the fetal brain than in the adult brain.
Defects in ANO10 are the cause of spinocerebellar ataxia autosomal recessive type 10 (SCAR10)
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Highly expressed in the brain. Intermediate levels in the retina and heart and low levels in the placenta, liver, lung, duodenum, kidney, testis and spleen. In brain areas, highest expression in the frontal and occipital cortices and in the cerebellum. Lower expression in the fetal brain than in the adult brain.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Yang Y.D, et al. Nature 455:1210-1215(2008)
Limitation
For research use only
Code
OSA00178W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Anoctamin10.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00178W
$260USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to Anoctamin10
