Code
OSA00172W
$240USD
ID Tag
Rb1774-290412-WS
Immunogen
A synthetic peptide from aa region of 2-100 of human Anoctamin 6 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Transmembrane protein 16F, ANO6, TMEM16F
Target
FUNCTION: May act as a calcium-activated chloride channel. It is essential for calcium-dependent exposure of phosphatidylserine on the surface of activated platelets, a process necessary to trigger the clotting system.
Defects in ANO6 are the cause of Scott syndrome (SCTS).
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Katoh M, et al. Int. J. Oncol. 24:1345-1349(2004)
2. Yang Y.D, et al. Nature 455:1210-1215(2008)
3. Suzuki J, et al. Nature 468:834-838(2010)
Limitation
For research use only
Code
OSA00172W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Anoctamin 6.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.