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Code
OSA00171W
$240USD
ID Tag
Rb1773-290412-WS
Immunogen
A synthetic peptide from extracellular domain (aa region of 580-680) of human Anoctamin 5 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Gnathodiaphyseal dysplasia 1 protein, Transmembrane protein 16E, ANO5, GDD1, TMEM16E
Target
FUNCTION: May act as a calcium-activated chloride channel.
Defects in ANO5 are the cause of gnathodiaphyseal dysplasia (GDD).
Defects in ANO5 are the cause of limb-girdle muscular dystrophy type 2L (LGMD2L).
Defects in ANO5 are the cause of miyoshi muscular dystrophy type 3 (MMD3).
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue specificity: Highly expressed in brain, heart, kidney, lung, and skeletal muscle. Weakly expressed in bone marrow, fetal liver, placenta, spleen, thymus, osteoblasts and periodontal ligament cells.
Defects in ANO5 are the cause of gnathodiaphyseal dysplasia (GDD).
Defects in ANO5 are the cause of limb-girdle muscular dystrophy type 2L (LGMD2L).
Defects in ANO5 are the cause of miyoshi muscular dystrophy type 3 (MMD3).
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue specificity: Highly expressed in brain, heart, kidney, lung, and skeletal muscle. Weakly expressed in bone marrow, fetal liver, placenta, spleen, thymus, osteoblasts and periodontal ligament cells.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Tsutsumi S, et al. Am. J. Hum. Genet. 74:1255-1261(2004)
Limitation
For research use only
Code
OSA00171W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Anoctamin 5.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00171W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to Anoctamin 5
