Code
OST00378W
$240USD
ID Tag
Rb1751-020111-WS
Immunogen
A synthetic peptide from n-terminal region of mouse TRAK1 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Trafficking kinesin-binding protein 1, 106 kDa O-GlcNAc transferase-interacting protein
Target
FUNCTION: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Note: Predominantly associated with early endosome. The localization to early endosomes depends on its interaction with HRS.
TISSUE SPECIFICITY: High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.
Over-expressed in all investigated carcinomas, especially in gastric adenocarcinoma and signet-ring carcinoma and may serve as a marker of gastric cancer.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Iyer S.P.N, et al. J. Biol. Chem. 278:5399-5409(2003)
Limitation
For research use only
Code
OST00378W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity
Specific for TRAK1.
Spcs X-react.
Mouse, human, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.