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Code
OSC00252W
$240USD
ID Tag
Rb1755-260312-WS
Immunogen
A synthetic peptide from n-terminal region of human CXCR2 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, CD182, Cmkar2, Gpcr16, Il8rb
Target
FUNCTION: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Cerretti D.P, et al. Genomics 18:410-413(1993)
2. Mueller S.G, et al. J. Biol. Chem. 272:8207-8214(1997)
2. Mueller S.G, et al. J. Biol. Chem. 272:8207-8214(1997)
Limitation
For research use only
Related
products
products
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Code
OSC00252W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for CXCR2.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSC00252W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Rabbit antibody to CXCR2
