Code
OSA00167W
$240USD
ID Tag
Rb1732-020111-WS
Immunogen
A synthetic peptide from aa region 1130-1180 of human ATP13A2 (PARK9) conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Probable cation-transporting ATPase 13A2, ATP13A2, PARK9
Target
Involvement in disease: Defects in ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS). A rare form of autosomal recessive juvenile or early-onset, levodopa-responsive parkinsonism. In addition to typical parkinsonian signs, clinical manifestations of Kufor-Rakeb syndrome include behavioral problems, facial tremor, pyramidal tract dysfunction, supranuclear gaze palsy, and dementia.
Subcellular location: Membrane; Multi-pass membrane protein. Lysosome
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ramirez A, et al. Nat. Genet. 38:1184-1191(2006)
2. Behrens M.I, et al. Mov. Disord. 25:1929-1937(2010)
Limitation
For research use only
Code
OSA00167W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ATP13A2.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.