ALMS1 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSA00161W

$240USD

ID Tag

Rb1714-021210-W

Immunogen

A synthetic peptide from aa region 4100-4150 of human ALMS1 conjugated to blue carrier protein was used as the antigen.

Accession

ALMS1_HUMAN

Also known

Alstrom syndrome protein 1

Target

FUNCTION: Possible role in intracellular trafficking.
SUBCELLULAR LOCATION: Cytoplasm. Centrosome. Cell projection, cilium basal body. Note: Associated with centrosomes and basal body at the base of primary cilia. During mitosis localizes to both spindle poles.
TISSUE SPECIFICITY: Ubiquitously expressed.
DEVELOPMENTAL STAGE: Expressed at E7.5. At E8.0 expression is found in mesodermal- and ectodermal-derived layers. At E10.5 mainly detected in midbrain, hindbrain, forelimb and hindlimb. Also expressed at E15.5 and E18.5.
MISCELLANEOUS: Mice lacking Alms1 display obesity, hypogonadism, hyperinsulinemia, retinal dysfunction and hearing loss.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Hearn T, et al. Nat. Genet. 31:79-83(2002)
2. Knorz V.J, et al. Mol. Biol. Cell 21:3617-3629(2010)

Limitation

For research use only

Code

OSA00161W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Specificity

Specific for ALMS1.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSA00161W