Code
OSP00165W
$240USD
ID Tag
Rb1695-021210-WS
Immunogen
A synthetic peptide from n-terminal region of mouse PITX1 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1, BFT, PTX1
Target
FUNCTION: May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
Defects in PITX1 are a cause of congenital clubfoot (CCF).
SUBCELLULAR LOCATION: Nucleus
TISSUE SPECIFICITY: Expressed in primordial Rathke pouch, oral epithelium, first branchial arch, duodenum, and hindlimb.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Shang J, et al. Genomics 40:108-113(1997)
2. Gurnett C.A, et al. Am. J. Hum. Genet. 83:616-622(2008)
Limitation
For research use only
Code
OSP00165W
$240USD
Unit size
150 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity
Specific for PITX1.
Spcs X-react.
Mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 150 µl of MQ water. Centrifuge to remove any insoluble material.