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Code
OSP00158W
$240USD
ID Tag
Rb1645-211110-WS
Immunogen
A synthetic peptide from 4th cytoplasmic region of human KCND2 (Kv4.2) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2
Target
Function: Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell projection ⺠dendrite. Note: Detected in dendrites in cultured hippocampal neurons. Association with KCNIP2 probably enhances cell surface expression.
Tissue specificity: Highly expressed throughout the brain. Expression is very low or absent in other tissues.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell projection ⺠dendrite. Note: Detected in dendrites in cultured hippocampal neurons. Association with KCNIP2 probably enhances cell surface expression.
Tissue specificity: Highly expressed throughout the brain. Expression is very low or absent in other tissues.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Isbrandt D, et al. Genomics 64:144-154(2000)
2. El-Haou S, et al. Circ. Res. 104:758-769(2009)
2. El-Haou S, et al. Circ. Res. 104:758-769(2009)
Limitation
For research use only
Code
OSP00158W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 200 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCND2.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSP00158W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to KCND2
