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Code
OSV00092W
$260USD
ID Tag
Ch4-151010-WS
Immunogen
A synthetic peptide from aa region 450-505 of human VACHT conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
Accession
Also known
Vesicular acetylcholine transporter, solute carrier family 18 member 3, SLC18A3, MGC12716
Target
FUNCTION: Involved in acetylcholine transport into synaptic vesicles.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: High expression in all major cholinergic cell groups, including peripheral postganglionic parasympathetic cells, preganglionic sympathetic and parasympathetic cells, ventral spinal cord and brainstem motoneurons, cell groups in the basal forebrain, the habenula and the corpus striatum. Weakly expressed in the cortex and hippocampus.
VACHT is also present in the olfactory bulb, nucleus of the lateral olfactory tract, olfactory tubercle.
SIMILARITY: Belongs to the major facilitator superfamily. Vesicular transporter family.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: High expression in all major cholinergic cell groups, including peripheral postganglionic parasympathetic cells, preganglionic sympathetic and parasympathetic cells, ventral spinal cord and brainstem motoneurons, cell groups in the basal forebrain, the habenula and the corpus striatum. Weakly expressed in the cortex and hippocampus.
VACHT is also present in the olfactory bulb, nucleus of the lateral olfactory tract, olfactory tubercle.
SIMILARITY: Belongs to the major facilitator superfamily. Vesicular transporter family.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ichikawa T, et al. J Chem Neuroanat. 13(1):23-39(1997).
Limitation
For research use only
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Code
OSV00092W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
Chicken
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for VACHT.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSV00092W
$260USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Chicken antibody to VACHT (450-505)
