Code
OST00367G
$240USD
ID Tag
Rb1623-211110-G
Immunogen
A synthetic peptide from n-terminal region of human T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1, TIAM1) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
TIAM-1, TIAM1
Target
FUNCTION: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
SUBUNIT: Interacts with BAIAP2.
TISSUE SPECIFICITY: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Habets G.G.M, et al. Oncogene 10:1371-1376(1995).
2. Sjoeblom T, et al. Science 314:268-274(2006).
Limitation
For research use only
Related
products
Code
OST00367G
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for TIAM1.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.