CLCN1 antibody, Chloride channel protein 1 antibody, ClC-1 antibody, CLC1 antibody

Primary Antibodies

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSC00245W

$240USD

ID Tag

Rb1683-021210-WS

Immunogen

A synthetic peptide from the c-terminal region of mouse Chloride channel protein 1 (CLCN1) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

CLCN1_MOUSE
CLCN1_RAT

Also known

Skeletal muscle Chloride channel protein 1, ClC-1, CLCN1, CLC1

Target

FUNCTION: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The absence of conserved gating glutamate residues is typical for family members that function as channels.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Predominantly expressed in skeletal muscles.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Schnuelle V, et al. Mamm. Genome 8:718-725(1997)
2. Steinmeyer K, et al. Nature 354:304-308(1991)
3. Gronemeier M, et al. J. Biol. Chem. 269:5963-5967(1994)

Limitation

For research use only

Code

OSC00245W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for CLCN1.

Spcs X-react.

Mouse, rat. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSC00245W