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Code
OSP00152W
$240USD
ID Tag
Rb2730-080516-WS
Immunogen
A synthetic peptide from internal region of mouse KCNJ8 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and human.
Accession
Also known
IRK8, ATP-sensitive inward rectifier potassium channel 8, Potassium channel, inwardly rectifying subfamily J member 8, Inwardly rectifier K(+) channel Kir6.1, uKATP-1
Target
FUNCTION: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.
Subcellular location: Membrane, Multi-pass membrane protein.
Subcellular location: Membrane, Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Inagaki N, et al. Genomics 30:102-104(1995)
Limitation
For research use only
- Click to download the Data Sheet
⚬ Products
Rabbit antibody to KCNJ8
