Code
OSS00298W
$240USD
ID Tag
Rb1616-120910-WS
Immunogen
A synthetic peptide from aa region 20-70 of mouse SLC12A5 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and shares 95% identity with human sequence.
Accession
Also known
Solute carrier family 12 member 5, Electroneutral potassium-chloride cotransporter 2, K-Cl cotransporter 2, Neuronal K-Cl cotransporter, SLC12A5, S12A5
Target
Function: Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl- homeostasis in neurons.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein
Tissue specificity: Brain specific. Detected in neuronal cells.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Uvarov P, et al. J. Biol. Chem. 282:30570-30576(2007)
Limitation
For research use only
Code
OSS00298W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC12A5.
Spcs X-react.
Mouse, rat. Other species not yet tested but expected to work in human.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.