Code
OSA00147W
$240USD
ID Tag
Rb1577-120910-WS
Immunogen
A synthetic peptide from cytoplasmic domain of mouse ADAM22 (Metalloproteinase-disintegrin ADAM22-3) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Disintegrin and metalloproteinase domain-containing protein 22, Metalloproteinase disintegrin ADAM22-3, Metalloproteinase like, disintegrin like, and cysteine-rich protein 2, MDC2
Target
FUNCTION: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein
TISSUE SPECIFICITY: Highly expressed in the brain and in some high-grade but not low-grade gliomas. Detected slightly or not at all in other tissues.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Sagane K, et al. Biochem. J. 334:93-98(1998)
2. Poindexter K, et al. Gene 237:61-70(1999)
Limitation
For research use only
Code
OSA00147W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ADAM22.
Spcs X-react.
Mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.