Code
OSS00284W
$240USD
ID Tag
Rb1527-130810-WS
Immunogen
A synthetic peptide from solcar 2 region of human Graves disease carrier protein (SLC25A16) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
GDC, Graves disease autoantigen, GDA, Mitochondrial solute carrier protein homolog, Solute carrier family 25 member 16, SLC25A16
Target
FUNCTION: Required for the accumulation of coenzyme A in the mitochondrial matrix. The protein has a possible role in Graves disease; GDC is recognised by autoantibody from patients with active Grave disease.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Zarrilli R, et al. Mol. Endocrinol. 3:1498-1505(1989)
2. Fiermonte G, et al. DNA Seq. 3:71-78(1992)
3. Prohl C, et al. Mol. Cell. Biol. 21:1089-1097(2001)
Limitation
For research use only
Code
OSS00284W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC25A16.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.