Code
OSS00276W
$260USD
ID Tag
Rb1520-130810-WS
Immunogen
A synthetic peptide from 1t cytoplasmic domain of human SLC45A2 (Melanoma antigen AIM1) conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Membrane associated transporter protein, Melanoma antigen AIM1, Protein AIM-1, Solute carrier family 45 member 2, MATP
Target
Function: Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis.
Defects in SLC45A2 are the cause of albinism oculocutaneous type 4 (OCA4)
. A disorder of pigmentation characterized by reduced biosynthesis of melanin in the skin, hair and eyes. Patients show reduced or lacking pigmentation associated with classic albinism ocular abnormalities, including decreased visual acuity, macular hypoplasia, optic dysplasia, atypical choroidal vessels, and nystagmus.
Tissue specificity: Expressed in most melanoma cell lines and melanocytes.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Harada M, et al. Cancer Res. 61:1089-1094(2001)
Limitation
For research use only
Related
products
Code
OSS00276W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC45A2.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.