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Code
OSS00270W
$240USD
ID Tag
Rb1515-130810-WS
Immunogen
A synthetic peptide from c-terminal region of human SLC47A2 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
MATE-2, Kidney-specific H(+)/organic cation antiporter, Solute carrier family 47 member 2, SLC47A2, MATE2
Target
FUNCTION: Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein Potential. Note: Localized at the brush border membranes of the proximal tubules.
Tissue specificity: Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein Potential. Note: Localized at the brush border membranes of the proximal tubules.
Tissue specificity: Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Masuda S, et al. J. Am. Soc. Nephrol. 17:2127-2135(2006)
2. Omote H, et al. Trends Pharmacol. Sci. 27:587-593(2006)
3. Tanihara Y, et al. Biochem. Pharmacol. 74:359-371(2007)
2. Omote H, et al. Trends Pharmacol. Sci. 27:587-593(2006)
3. Tanihara Y, et al. Biochem. Pharmacol. 74:359-371(2007)
Limitation
For research use only
Code
OSS00270W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC47A2.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00270W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to SLC47A2
