Code
OSV00091W
$240USD
ID Tag
Rb1593-120910-WS
Immunogen
A synthetic peptide from internal region of human VGCNL1 (Voltage gated channel like protein 1) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
NALCN, Sodium leak channel non-selective protein, Voltage gated channel-like protein 1
Target
Function: Voltage-independent, cation-nonselective channel which is permeable to sodium, potassium and calcium ions. Responsible for the background sodium ion leak current in neurons and controls neuronal excitability. Activated either by neuropeptides substance P or neurotensin. Required for normal respiratory rhythm and neonatal survival.
Tissue specificity: Widely expressed in the brain and spinal cord neurons.
Subcellular location: Membrane; Multi-pass membrane protein
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Chumakov I, et al. Proc. Natl. Acad. Sci. U.S.A. 99:13675-13680(2002)
2. Lu B, et al. Cell 129:371-383(2007)
Limitation
For research use only
Related
products
Code
OSV00091W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 200 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for VGCNL1.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.