VGCNL1 antibody, Voltage gated channel like protein 1 antibody, Sodium leak channel non selective protein antibody

Primary Antibodies

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSV00090W

$240USD

ID Tag

Rb1592-120910-WS

Immunogen

A synthetic peptide from internal region of mouse VGCNL1 (Voltage gated channel like protein 1) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

VGCNL1_MOUSE

Also known

NALCN, Sodium leak channel non-selective protein, Voltage gated channel-like protein 1

Target

Function: Voltage-independent, cation-nonselective channel which is permeable to sodium, potassium and calcium ions. Responsible for the background sodium ion leak current in neurons and controls neuronal excitability. Activated either by neuropeptides substance P or neurotensin. Required for normal respiratory rhythm and neonatal survival.
Tissue specificity: Widely expressed in the brain and spinal cord neurons.
Subcellular location: Membrane; Multi-pass membrane protein

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Lu B, et al. Cell 129:371-383(2007)
2. Lu B, et al. Nature 457:741-744(2009)

Limitation

For research use only