Mitofusin 1 antibody, Transmembrane GTPase MFN1 antibody, MFN1 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSM00100W

$240USD

ID Tag

Rb1590-120910-WS

Immunogen

A synthetic peptide from n-terminal region of mouse Mitofusin 1 (Transmembrane GTPase MFN1) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

MFN1_MOUSE
MFN1_RAT

Also known

Transmembrane GTPase MFN1, MFN1

Target

FUNCTION: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
MFN1 deficient mice die early during embryonic development, due to altered mitochondria morphology, which are fragmented, showing that mitochondrial fusion is essential for embryonic development.
SUBCELLULAR LOCATION: Mitochondrion outer membrane; Multi-pass membrane protein
Tissue specificity: Widely expressed

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Chen H, et al. J. Cell Biol. 160:189-200(2003)
2. Rojo M, et al. J. Cell Sci. 115:1663-1674(2002)

Limitation

For research use only

Code

OSM00100W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for Mitofusin-1.

Spcs X-react.

Mouse. Not yet tested in other species but expected to work in rat.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSM00100W