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Code
OSS00261W
$240USD
ID Tag
Rb1540-130810-WS
Immunogen
A synthetic peptide from c-terminal region of human SLC22A8 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Solute carrier family 22 member 8, OAT3, SLC22A8
Target
FUNCTION: Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
SUBCELLULAR LOCATION: Basolateral cell membrane; Multi-pass membrane protein Potential. Note: Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC)
TISSUE SPECIFICITY: Highly expressed in kidney. Expressed in developing bone. Weakly expressed in brain and eye.
SUBCELLULAR LOCATION: Basolateral cell membrane; Multi-pass membrane protein Potential. Note: Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC)
TISSUE SPECIFICITY: Highly expressed in kidney. Expressed in developing bone. Weakly expressed in brain and eye.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Race J.E, et al. Biochem. Biophys. Res. Commun. 255:508-514(1999)
Limitation
For research use only
Code
OSS00261W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC22A8.
Spcs X-react.
Human, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
- Click to see the eLab Book
Code
OSS00261W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSS00261W
$240USD
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WB on marmoset brain lysate. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:1000 incubated at 4C overnight. Click on eLAB BOOK tab to see the details. |
⚬ Products
Rabbit antibody to SLC22A8
