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Code
OSM00093W
$240USD
ID Tag
Rb1585-120910-WS
Immunogen
A synthetic peptide from human pro MMP9 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
pro Matrix Metalloproteinase-9, MMP-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, CLG4B
Target
FUNCTION: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
SUBCELLULAR LOCATION: Secreted ⺠extracellular space ⺠extracellular matrix
TISSUE SPECIFICITY: Produced by normal alveolar macrophages and granulocytes. MMP9 is constitutively expressed by some tumor cell lines including U937, HT1080, HL60 but not by most quiescent cells and tissues.
SUBCELLULAR LOCATION: Secreted ⺠extracellular space ⺠extracellular matrix
TISSUE SPECIFICITY: Produced by normal alveolar macrophages and granulocytes. MMP9 is constitutively expressed by some tumor cell lines including U937, HT1080, HL60 but not by most quiescent cells and tissues.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Wilhelm S.M, et al. J. Biol. Chem. 264:17213-17221(1989)
2. Huhtala P, et al. J. Biol. Chem. 266:16485-16490(1991)
2. Huhtala P, et al. J. Biol. Chem. 266:16485-16490(1991)
Limitation
For research use only
Code
OSM00093W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for pro Matrix Metalloproteinase-9
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSM00093W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to pro MMP9
