SOX2 antibody, Transcription factor SOX-2 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSS00251W

$240USD

ID Tag

Rb1828-120812-WS

Immunogen

A synthetic peptide from aa region of 10-70 of mouse SOX2 conjugated to an immunogenic carrier protein was used as the antigen.

Accession

SOX2_MOUSE
SOX2_RAT
SOX2_HUMAN

Also known

Transcription factor SOX-2, Sox-2

Target

FUNCTION: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Subcellular location: Nucleus
Tissue specificity: Expressed in the brain and retina. A very low level expression is seen in the stomach and lung. Expressed in developing urogenital ridge.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Collignon J, et al. Development 122:509-520(1996)
2. Yu H.B, et al. J. Biol. Chem. 284:31327-31335(2009)
3. Fantes J, et al. Nat. Genet. 33:461-463(2003)

Limitation

For research use only

Related
products

Code	Product Name
OSS00322W	Rabbit antibody to SOX2

Code

OSS00251W

$240USD

Unit size

150 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for SOX2.

Spcs X-react.

Mouse, rat, human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSS00251W