Rb1581-120910-WS

A synthetic peptide from cytoplasmic domain of mouse LRFN1 (Synaptic differentiation enhancing molecule 1) conjugated to an immunogenic carrier protein was used as the antigen.

LRFN1_MOUSE
LRFN1_RAT

Leucine rich repeat and fibronectin type III domain containing protein 1, Synaptic adhesion like molecule 2, Synaptic differentiation enhancing molecule 1, SALM2, SEMO1

FUNCTION: Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1.
Subcellular location: Membrane; Single-pass type I membrane protein. Cell junction › synapse. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density. Note: Detected in excitatory, but not inhibitory, synaptic plasma membrane
Tissue specificity: Predominantly expressed in the brain, with a weak, but broad expression in the cerebral cortex and diencephalic nuclei. Also detected in other parts of the central nervous system, including the olfactory bulb, pons, cerebellum, and medulla oblongata, as well as in the peripheral nervous system, such as the ganglia of cranial nerves and the dorsal root ganglion during gestation.

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. Morimura N, et al. Gene 380:72-83(2006)
2. Wang P.Y, et al. Mol. Cell. Neurosci. 39:83-94(2008)

For research use only

100 µl

Unconjugated antibody

NZ white rabbit

Whole serum

Polyclonal

Polyclonal, whole serum

IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specific for LRFN1.

Mouse, rat. Other species not yet tested.

Lyophilised

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

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- Click to download the Material Safety Data Sheet