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Code
OSM00092W
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ID Tag
Rb1576-120910-WS

Immunogen
A synthetic peptide from internal region of mouse MAD3 (Max dimerization protein 3) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

Also known
Max dimerization protein 3, Max dimerizer 3, Class C basic helix-loop-helix protein 13, bHLHc13, Max-associated protein 3, Max-interacting transcriptional repressor MAD3, MXD3

Target
FUNCTION: Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Subcellular location: Nucleus
Tissue specificity: Expressed only in the proliferating areas of the testis and thymus.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Hurlin P.J, et al. EMBO J. 14:5646-5659(1995)
2. Queva C, et al. Mol. Cell. Biol. 21:703-712(2001)

Limitation
For research use only

⚬ Products
Rabbit antibody to MAD3
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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