Code
OST00360W
$260USD
ID Tag
Gt253-180710-WS
Immunogen
A synthetic peptide from aa region 780-835 of rat TRPC3 conjugated to blue carrier protein was used as the antigen.
The location of the epitope is highlighted in
green.

Accession
Also known
Short transient receptor potential channel 3, transient receptor potential cation channel, subfamily C, member 3
Target
FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ohki G, et al. J. Biol. Chem. 275:39055-39060(2000).
Limitation
For research use only
Code
OST00360W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
Goat
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for TRPC3.
Spcs X-react.
Rat, mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.