P2Y1 antibody, P2RY2 antibody, Purinergic receptor antibody, P2Y purinoceptor 1 antibody

Primary Antibodies

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSP00121W

$240USD

ID Tag

Rb1428-250410-WS

Immunogen

A synthetic peptide from the extracellular domain of human P2Y1 (P2RY1) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

P2RY1_HUMAN
P2RY1_RAT
P2RY1_GUINEA PIG

Also known

P2Y purinoceptor 1, P2Y1, Purinergic receptor, ATP receptor

Target

FUNCTION: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Repressed by the P2Y1 receptor-specific antagonists A3P5PS, A3P5P and A2P5P. These inhibit calcium ion mobilization and shape change in platelets.
Subcellular location: Membrane; Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Leon C, et al. Gene 171:295-297(1996)
2. Zahedi R.P, et al. J. Proteome Res. 7:526-534(2008)

Limitation

For research use only

Code

OSP00121W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for P2RY1.

Spcs X-react.

Human, guinea pig. Other species not yet tested but expected to work in rat.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSP00121W