P2Y1 antibody, P2RY2 antibody, Purinergic receptor antibody, P2Y purinoceptor 1 antibody

Primary Antibodies

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSP00120W

$240USD

ID Tag

Rb1427-250410-WS

Immunogen

A synthetic peptide from the internal region of mouse P2Y1 (P2RY1) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

P2RY1_MOUSE

Also known

P2Y purinoceptor 1, P2Y1, Purinergic receptor, ATP receptor

Target

FUNCTION: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Repressed by the P2Y1 receptor-specific antagonists A3P5PS, A3P5P and A2P5P. These inhibit calcium ion mobilization and shape change in platelets.
Subcellular location: Membrane; Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Tokuyama Y, et al. Biochem. Biophys. Res. Commun. 211:211-218(1995)
2. Leon C, et al. J. Clin. Invest. 104:1731-1737(1999)

Limitation

For research use only

Code

OSP00120W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for P2RY1.

Spcs X-react.

Mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSP00120W