Code
OSL00013W
$240USD
ID Tag
Rb1366-140310-WS
Immunogen
A synthetic peptide from 1t extracellular domain of human Latrophilin-1 (LPHN1) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
LPHN1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, Lectomedin-2, Lectomedin 2, LEC2
Target
FUNCTION: Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis.
TISSUE SPECIFICITY: Brain specific distribution but low levels are also detected in most tissues.
Subcellular location: Cell membrane; Multi-pass membrane protein
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Brill L.M, et al. Anal. Chem. 76:2763-2772(2004)
2. Vassilatis D.K, et al. Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003)
3. Munton R.P, et al. Mol. Cell. Proteomics 6:283-293(2007)
Limitation
For research use only
Code
OSL00013W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for LPHN1.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.