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Code
OSP00110W
$240USD
ID Tag
Rb1373-140310-WS
Immunogen
A synthetic peptide from n-terminal region of human PCM1 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Pericentriolar material 1 protein, PCM-1
Target
FUNCTION: Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. Required to anchor microtubules to the centrosome.
Tissue specificity: Expressed in blood, bone marrow, breast, lymph node, ovary and thyroid.
Subcellular location: Cytoplasm ⺠cytoskeleton. Cytoplasm ⺠cytoskeleton ⺠centrosome. Cytoplasmic granule. Note: Localizes to cytoplasmic granules which are enriched around the centrosome. This centrosomal enrichment requires microtubules and dynein. The majority of the protein dissociates from the centrosome during metaphase and subsequently localizes to the cleavage site in telophase.
Tissue specificity: Expressed in blood, bone marrow, breast, lymph node, ovary and thyroid.
Subcellular location: Cytoplasm ⺠cytoskeleton. Cytoplasm ⺠cytoskeleton ⺠centrosome. Cytoplasmic granule. Note: Localizes to cytoplasmic granules which are enriched around the centrosome. This centrosomal enrichment requires microtubules and dynein. The majority of the protein dissociates from the centrosome during metaphase and subsequently localizes to the cleavage site in telophase.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Balczon R, et al. J. Cell Biol. 124:783-793(1994)
Limitation
For research use only
Code
OSP00110W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for PCM1.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSP00110W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to PCM1
