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Code
OSG00070W
$240USD
ID Tag
Rb1347-140310-WS
Immunogen
A synthetic peptide from c-terminal region of mouse Neuroleukin (GPI) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
G6PI, Glucose-6-phosphate isomerase, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Autocrine motility factor, AMF, NLK
Target
FUNCTION: Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.
Defects in GPI are a cause of hereditary nonspherocytic hemolytic anemia (HA). Severe GPI deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
SUBCELLULAR LOCATION: Cytoplasm. Secreted
Defects in GPI are a cause of hereditary nonspherocytic hemolytic anemia (HA). Severe GPI deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
SUBCELLULAR LOCATION: Cytoplasm. Secreted
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Gurney M.E, et al. Science 234:566-574(1986)
2. Tanaka N, et al. J. Mol. Biol. 356:312-324(2006)
2. Tanaka N, et al. J. Mol. Biol. 356:312-324(2006)
Limitation
For research use only
Code
OSG00070W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Neuroleukin.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSG00070W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to Neuroleukin
