Code
OSP00108W
$240USD
ID Tag
Rb1345-140310-WS
Immunogen
A synthetic peptide from internal region of mouse PPM1D conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
PPM1D, Protein phosphatase 2C isoform delta, PP2C-delta, p53-induced protein phosphatase 1, Protein phosphatase magnesium-dependent 1 delta
Target
FUNCTION: Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-18' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
Tissue specificity: Ubiquitously expressed.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Choi J, et al. Genomics 64:298-306(2000)
Limitation
For research use only
Code
OSP00108W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity
Specific for PPM1D.
Spcs X-react.
Mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.