Code
OSR00356W
$240USD
ID Tag
Rb1283-140210-WS
Immunogen
A synthetic peptide from 120-170 of human Repulsive guidance molecule B (RGMB) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
RGMB, RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON
Target
FUNCTION: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system. Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling. Promotes neuronal adhesion. May inhibit neurite outgrowth.
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor ⺠GPI-anchor. Membrane raft
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ota T, et al. Nat. Genet. 36:40-45(2004)
2. Liu X, et al. Biochem. Biophys. Res. Commun. 382:795-800(2009)
Limitation
For research use only
Code
OSR00356W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity
Specific for RGMB.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.