Code
OSN00048W
$240USD
ID Tag
Rb1277-140210-WS
Immunogen
A synthetic peptide from aa region 2400-2450 of human Neuron navigator 2 (NAV2, Steerin-2) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
NAV2, Helicase APC down-regulated 1, Retinoic acid inducible in neuroblastoma 1, Steerin-2, Pore membrane and/or filament-interacting-like protein 2, Unc-53 homolog 2, unc53H2, HELAD1, KIAA1419, POMFIL2, RAINB1
Target
FUNCTION: Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
SUBCELLULAR LOCATION: Nucleus
TISSUE SPECIFICITY: Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Merrill R.A, et el. Proc. Natl. Acad. Sci. U.S.A. 99:3422-3427(2002)
2. Ishiguro H, et al. Oncogene 21:6387-6394(2002)
Limitation
For research use only
Code
OSN00048W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity
Specific for NAV2.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.