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Code
OSB00044W
$240USD
ID Tag
Rb1258-140210-WS
Immunogen
A synthetic peptide from n-terminal region of human CAP 57 (BPI) conjugated to an immunogenic carrier protein has been used as the antigen.
Accession
Also known
Bactericidal permeability-increasing protein, BPI
Target
Function: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Subcellular location: Secreted. Cytoplasmic granule membrane. Note: Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Tissue specificity: Restricted to cells of the myeloid series.
Subcellular location: Secreted. Cytoplasmic granule membrane. Note: Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Tissue specificity: Restricted to cells of the myeloid series.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Gray P.W, et al. J. Biol. Chem. 264:9505-9509(1989)
2. Wilde C.G, et al. J. Biol. Chem. 269:17411-17416(1994)
2. Wilde C.G, et al. J. Biol. Chem. 269:17411-17416(1994)
Limitation
For research use only
Code
OSB00044W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. Use at a dilution of 1:100 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for BPI.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSB00044W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to BPI
