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Code
OSI00002W
$240USD
ID Tag
Rb1209-051209-WS
Immunogen
A synthetic peptide from the internal region of mouse ISLR2 (Linx) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Immunoglobulin superfamily containing leucine-rich repeat protein 2, Linx, Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein
Target
FUNCTION: Required for axon extension during neural development.
SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein
TISSUE SPECIFICITY: At E11.5, expressed in spinal nerves, their roots and the ventral spinal cord. At E12.5, detected in the ventral spinal cord, dorsal root ganglia (DRG), dorsal and ventral roots and sympathetic chain ganglia. At E12.5, expressed in almost all motor neurons which also express RET and in almost all DRG sensory neurons which also express NTRK1. At E18.5, expressed only in a subset of NTRK1-expressing neurons but still expressed in nearly all RET-expressing neurons.
SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein
TISSUE SPECIFICITY: At E11.5, expressed in spinal nerves, their roots and the ventral spinal cord. At E12.5, detected in the ventral spinal cord, dorsal root ganglia (DRG), dorsal and ventral roots and sympathetic chain ganglia. At E12.5, expressed in almost all motor neurons which also express RET and in almost all DRG sensory neurons which also express NTRK1. At E18.5, expressed only in a subset of NTRK1-expressing neurons but still expressed in nearly all RET-expressing neurons.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Mandai K, et al. Neuron 63:614-627(2009)
2. Okazaki N, et al. DNA Res. 10:167-180(2003)
2. Okazaki N, et al. DNA Res. 10:167-180(2003)
Limitation
For research use only
Code
OSI00002W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity
Specific for ISLR2.
Spcs X-react.
Mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSI00002W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to ISLR2
