Code
OSC00206W
$240USD
ID Tag
Rb1224-051209-WS
Immunogen
A synthetic peptide from the n-terminal region of human Extracellular calcium-sensing receptor (CaSR) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
CASR, CaSR, Parathyroid cell calcium-sensing receptor, PCaR1, GPRC2A, PCAR1
Target
Function: Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Tissue specificity: Expressed in the temporal lobe, frontal lobe, parietal lobe, hippocampus, and cerebellum. Also found in kidney, lung, liver, heart, skeletal muscle, placenta.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Garrett J.E, et al. J. Biol. Chem. 270:12919-12925(1995)
2. Kapoor A, et al. Ann. Neurol. 64:158-167(2008)
Limitation
For research use only
Code
OSC00206W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for CASR.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.