Rb1218-051209-WS

A synthetic peptide from n-terminal region of human SNAPIN (SNARE associated protein Snapin) conjugated to an immunogenic carrier protein was used as the antigen.

SNAPIN_HUMAN
SNAPIN_MOUSE
SNAPIN_RAT

SNAPN, SNARE-associated protein Snapin, Synaptosomal-associated protein 25-binding protein, SNAP-associated protein, SNAP25BP, SNAPAP

Function: May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release by potentiating the interaction of synaptotagmins with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells.
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side Potential. Cell junction › synapse › synaptosome. Note: May be cytoplasmic and peripheral membrane bound or anchored to the vesicular membrane through an N-terminal signal anchor
Tissue specificity: Strongly expressed in heart, brain, testis, kidney and liver; low expression in spleen, lung and skeletal muscle.

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. Ilardi J.M, et al. Nat. Neurosci. 2:119-124(1999)
2. Ota T, et al. Nat. Genet. 36:40-45(2004)
3. Mayya V, et al. Sci. Signal. 2:RA46-RA46(2009)

For research use only

100 µl

Unconjugated antibody

NZ white rabbit

Whole serum

Polyclonal

Polyclonal, whole serum

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specific for SNAPIN.

Human, rat, mouse. Other species not yet tested.

Lyophilised

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

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- Click to download the Material Safety Data Sheet