|
|
Code
OSP00103W
$240USD
ID Tag
Rb1250-051209-WS
Immunogen
A synthetic peptide from the internal region of human KCNB1 (Voltage gated potassium channel subunit Kv2.1) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Potassium voltage-gated channel subfamily B member 1, Voltage-gated potassium channel subunit Kv2.1, Delayed rectifier potassium channel 1, DRK1, h-DRK1
Target
Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.
Tissue specificity: In the brain, the greatest density occurs in the cerebral cortex, followed by the hippocampus, cerebellum, and olfactory bulb. In peripheral tissues it is most prominent in retina and kidney. Also present in cardiac muscle tissue of the atrium and ventricle and in skeletal muscle.
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: In the brain, the greatest density occurs in the cerebral cortex, followed by the hippocampus, cerebellum, and olfactory bulb. In peripheral tissues it is most prominent in retina and kidney. Also present in cardiac muscle tissue of the atrium and ventricle and in skeletal muscle.
Subcellular location: Membrane; Multi-pass membrane protein
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Albrecht B, et al. Recept. Channels 1:99-110(1993)
2. Ikeda S.R, et al. Pflugers Arch. 422:201-203(1992)
3. Deloukas P, et al. Nature 414:865-871(2001)
2. Ikeda S.R, et al. Pflugers Arch. 422:201-203(1992)
3. Deloukas P, et al. Nature 414:865-871(2001)
Limitation
For research use only
Code
OSP00103W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNB1.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSP00103W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to KCNB1
