Code
OSC00203W
$240USD
ID Tag
Rb1196-051209-WS
Immunogen
A synthetic peptide from the c-terminal region of human Cation channel sperm associated protein 3 (CATSPER3) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
CTSR3, CatSper3, CATSPER3, One-repeat calcium channel-like protein, Ca(v)-like protein
Target
Function: Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization.
Subcellular location: Cell projection ⺠cilium ⺠flagellum membrane; Multi-pass membrane protein
Tissue specificity: Testis-specific. Specifically present in the principal piece of sperm tail.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Arias J.M, et al. Biochem. Biophys. Res. Commun. 303:31-36(2003)
2. Lobley A, et al. Reprod. Biol. Endocrinol. 1:53-53(2003)
3. Li H.-G, et al. Mol. Hum. Reprod. 13:299-306(2007)
Limitation
For research use only
Code
OSC00203W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for CATSPER3.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.