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Code
OSC00194W
$260USD
ID Tag
Gt206-101009-WS
Immunogen
A synthetic peptide from the c-terminal region of human Calreticulin (Calregulin) conjugated to blue carrier protein was used as the antigen.
Accession
Also known
CALR, CRP55, Calregulin, HACBP, ERp60, grp60, CRTC
Target
FUNCTION: Molecular calcium binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export.
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen. Cytoplasm ⺠cytosol. Secreted ⺠extracellular space ⺠extracellular matrix. Cell surface. Note: Also found in cell surface (T cells), cytosol and extracellular matrix. Associated with the lytic granules in the cytolytic T-lymphocytes.
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen. Cytoplasm ⺠cytosol. Secreted ⺠extracellular space ⺠extracellular matrix. Cell surface. Note: Also found in cell surface (T cells), cytosol and extracellular matrix. Associated with the lytic granules in the cytolytic T-lymphocytes.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. McCauliffe D.P, et al. J. Clin. Invest. 85:1379-1391(1990)
Limitation
For research use only
Code
OSC00194W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
Goat
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Calreticulin.
Spcs X-react.
Human, rat, mouse. Not yet tested in other species.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSC00194W
$260USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Goat antibody to Calreticulin
