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Code
OSS00208W
$260USD
ID Tag
Gt201-101009-WS
Immunogen
A synthetic peptide from the internal region of human SHANK3 (SH3 and multiple ankyrin repeat domains protein 3, ProSAP2) conjugated to blue carrier protein was used as the antigen.
Accession
Also known
SH3 and multiple ankyrin repeat domains protein 3, ProSAP2, Proline rich synapse associated protein 2, PSAP2
Target
Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Subcellular location: Cytoplasm. Cell junction ⺠synapse. Cell junction ⺠synapse ⺠postsynaptic cell membrane ⺠postsynaptic density. Note: Postsynaptic density of neuronal cells. Extends into the region subjacent to the PSD.
Tissue specificity: Widely expressed in brain.
Subcellular location: Cytoplasm. Cell junction ⺠synapse. Cell junction ⺠synapse ⺠postsynaptic cell membrane ⺠postsynaptic density. Note: Postsynaptic density of neuronal cells. Extends into the region subjacent to the PSD.
Tissue specificity: Widely expressed in brain.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Dunham I, et al. ature 402:489-495(1999)
Limitation
For research use only
Code
OSS00208W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
Goat
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SHANK3.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00208W
$260USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Goat antibody to SHANK3
